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BioMed Research International
Volume 2014, Article ID 421964, 7 pages
http://dx.doi.org/10.1155/2014/421964
Clinical Study

Early Stage Oropharyngeal Carcinomas: Comparing Quality of Life for Different Treatment Modalities

Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstraße 1, 91054 Erlangen, Germany

Received 20 November 2013; Accepted 8 January 2014; Published 25 February 2014

Academic Editor: Jan Plzák

Copyright © 2014 Don-Felix Ryzek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. L. Gillison, “Current topics in the epidemiology of oral cavity and oropharyngeal cancers,” Head and Neck, vol. 29, no. 8, pp. 779–792, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Siegel, D. Naishadham, and A. Jemal, “Cancer statistics, 2012,” Cancer Journal for Clinicians, vol. 62, no. 1, pp. 10–29, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. G. Psychogios, K. Mantsopoulos, A. Agaimy et al., “Prognostic factors in limited (T1-2, N0-1) oropharyngeal carcinoma treated with surgery +/- adjuvant therapy,” Head & Neck, vol. 35, no. 12, pp. 1752–1758, 2013. View at Publisher · View at Google Scholar
  4. S. E. Mowry, A. Ho, M. M. LoTempio, A. Sadeghi, K. E. Blackwell, and M. B. Wang, “Quality of life in advanced oropharyngeal carcinoma after chemoradiation versus surgery and radiation,” Laryngoscope, vol. 116, no. 9, pp. 1589–1593, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. A. D. Karatzanis, G. Psychogios, F. Waldfahrer, J. Zenk, G. A. Velegrakis, and H. Iro, “Surgical management of T1 oropharyngeal carcinoma,” Head and Neck, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. G. Psychogios, K. Mantsopoulos, J. Kuenzel et al., “Primary surgical treatment of T2 oropharyngeal carcinoma,” Journal of Surgical Oncology, vol. 105, no. 7, pp. 719–723, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. A. S. Denittis, M. Machtay, D. I. Rosenthal et al., “Advanced oropharyngeal carcinoma treated with surgery and radiotherapy: oncologic outcome and functional assessment,” American Journal of Otolaryngology, vol. 22, no. 5, pp. 329–335, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. P. Friedlander, S. Caruana, B. Singh et al., “Functional status after primary surgical therapy for squamous cell carcinoma of the base of the tongue,” Head and Neck, vol. 24, no. 2, pp. 111–114, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. M. L. Robertson, L. L. Gleich, W. L. Barrett, and J. L. Gluckman, “Base-of-tongue cancer: survival, function, and quality of life after external-beam irradiation and brachytherapy,” Laryngoscope, vol. 111, no. 8, pp. 1362–1365, 2001. View at Google Scholar · View at Scopus
  10. A. C. Nichols, J. Yoo, J. A. Hammond et al., “Early-stage squamous cell carcinoma of the oropharynx: radiotherapy vs. trans-oral robotic surgery (ORATOR)—study protocol for a randomized phase II trial,” BMC Cancer, vol. 13, article 133, 2013. View at Google Scholar
  11. M. A. Broglie, A. Soltermann, S. R. Haile et al., “Quality of life of oropharyngeal cancer patients with respect to treatment strategy and p16-positivity,” The Laryngoscope, vol. 123, pp. 164–170, 2013. View at Google Scholar
  12. P. Boscolo-Rizzo, M. Stellin, R. Fuson, C. Marchiori, A. Gava, and M. C. D. Mosto, “Long-term quality of life after treatment for locally advanced oropharyngeal carcinoma: surgery and postoperative radiotherapy versus concurrent chemoradiation,” Oral Oncology, vol. 45, no. 11, pp. 953–957, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Tribius and C. Bergelt, “Intensity-modulated radiotherapy versus conventional and 3D conformal radiotherapy in patients with head and neck cancer: is there a worthwhile quality of life gain?” Cancer Treatment Reviews, vol. 37, no. 7, pp. 511–519, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. N. K. Aaronson, S. Ahmedzai, B. Bergman et al., “The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology,” Journal of the National Cancer Institute, vol. 85, no. 5, pp. 365–376, 1993. View at Google Scholar · View at Scopus
  15. K. Bjordal, E. Hammerlid, M. Ahlner-Elmqvist et al., “Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H and N35,” Journal of Clinical Oncology, vol. 17, no. 3, pp. 1008–1019, 1999. View at Google Scholar · View at Scopus
  16. U. Tschiesner, L. Schuster, S. Strieth, and U. Harréus, “Functional outcome in patients with advanced head and neck cancer: surgery and reconstruction with free flaps versus primary radiochemotherapy,” European Archives of Oto-Rhino-Laryngology, vol. 269, no. 2, pp. 629–638, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. R. R. Walvekar, R. J. Li, W. E. Gooding et al., “Role of surgery in limited (T1-2, N0-1) cancers of the oropharynx,” Laryngoscope, vol. 118, no. 12, pp. 2129–2134, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. H. Iro, K. Mantsopoulos, J. Zenk, F. Waldfahrer, and G. Psychogios, “Results of transoral laser resection in T1-2 oropharyngeal, hypopharyngeal and laryngeal carcinomas,” Laryngo-Rhino-Otologie, vol. 90, no. 8, pp. 481–485, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. K. K. Ang and E. M. Sturgis, “Human Papillomavirus as a marker of the natural history and response to therapy of head and neck squamous cell carcinoma,” Seminars in Radiation Oncology, vol. 22, no. 2, pp. 128–142, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. G. Psychogios, C. Alexiou, A. Agaimy et al., “Epidemiology and survival of HPV related tonsillar carcinoma,” Cancer Medicine. In press.
  21. G. F. Funk, L. H. Karnell, and A. J. Christensen, “Long-term health-related quality of life in survivors of head and neck cancer,” Archives of Otolaryngology, vol. 138, no. 2, pp. 123–133, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. T. Gunzel and M. Schimmer, “Quality of life after primary radiation/radiochemotherapy vs. operation therapy in an oropharyngeal cancer,” Laryngo-Rhino-Otologie, vol. 91, pp. 451–459, 2012. View at Google Scholar
  23. K. Bjordal, M. Ahlner-Elmqvist, E. Hammerlid et al., “A prospective study of quality of life in head and neck cancer patients. Part II: longitudinal data,” Laryngoscope, vol. 111, no. 8, pp. 1440–1452, 2001. View at Google Scholar · View at Scopus