Identification of a 20-Gene Expression-Based Risk Score as a Predictor of Clinical Outcome in Chronic Lymphocytic Leukemia Patients

Table 1

List of the 22 probe sets associated with a prognostic value in CLL patients.

Probe set	Gene symbol	Gene name	Hazard Ratio
218559_s_at	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B	0.0471
203413_at	NELL2	NEL-like 2	0.0481
212761_at	TCF7L2	transcription factor 7-like 2	0.0497
206157_at	PTX3	pentraxin 3, long	0.0537
219947_at	CLEC4A	C-type lectin domain family 4, member A	0.0566
209871_s_at	APBA2	amyloid beta precursor protein-binding, family A, member 2	0.0568
204526_s_at	TBC1D8	TBC1 domain family, member 8	0.063
218793_s_at	SCML1	sex comb on midleg-like 1	0.0636
225924_at	FNIP2	folliculin interacting protein 2	0.0638
207075_at	NLRP3	NLR family, pyrin domain containing 3	0.0663
221698_s_at	CLEC7A	C-type lectin domain family 7, member A	0.0667
226876_at	FAM101B	family with sequence similarity 101, member B	0.0691
212239_at	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.0731
203397_s_at	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.0739
216037_x_at	TCF7L2	transcription factor 7-like 2	0.0781
226279_at	PRSS23	protease, serine, 23	0.0833
229699_at	LOC100129550	hypothetical LOC100129550	0.0841
244598_at	LCP2	lymphocyte cytosolic protein 2	0.0907
209183_s_at	C10orf10	chromosome 10 open reading frame 10	14.5055
203720_s_at	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1	15.0143
203719_at	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1	15.6883
221725_at	WASF2	WAS protein family, member 2	16.2394

Hazard ratios (HR) are indicated for each gene used to design GE-based risk score in CLL patients. Probe sets are sorted by increasing HR.