The Longitudinal Assessment of Osteomyelitis Development by Molecular Imaging in a Rabbit Model
Figure 3
Bacterial culture and histology. (a) Postmortem bacterial culture of the excised part of the tibial tuberosity of the osteomyelitic tibia, indicating bacterial presence in all tibiae. (b) Histological confirmation of bacterial presence, by Gram stain, in the contaminated right leg only. (c) Bone morphological changes between left and right tibia. Tibial tuberosity is missing in the section of the right leg since this was used for bacterial culture. Fluorescence microscopy (insert) indicated normal bone remodelling in the left tibia, while it indicates cortex remodelling during the experimental follow-up in the right tibia (green at two weeks, red at four weeks, and blue at six weeks after surgery).
