Circadian Modulation of the Cl⁻ Equilibrium Potential in the Rat Suprachiasmatic Nuclei

Figure 3

𝐸_GABA distributions in the SCN. Comparison of all 𝐸_GABA values recorded in perforated patch configuration, grouped by SCN region (a) or ZT of recording (b). Values are shown in mean ± SEM. (c) Distribution of 𝐸_GABA separated by SCN region and ZT of recording. Experiments obtained in perforated patch configuration. (d) Statistically significant differences were found with Kruskal-Wallis test (H = 42.4, 𝑃<0.0001). Analysis was performed with the prevailing part of the groups depicted in (c). Dunn’s multiple comparison test indicated significant differences between the groups (𝑃<0.05). Distribution of 𝐸_GABA in neurons recorded in whole cell configuration with a theoretical 𝐸_Cl⁻ of −30 mV (e) and 𝐸_Cl⁻ of −60 mV (f).

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