New Researches and Application Progress of Commonly Used Optical Molecular Imaging Technology
Figure 3
Bioluminescence imaging of HSV-1 transgenic reporter mouse. Transgenic mouse with firefly luciferase controlled by the viral promoter for HSV-1 thymidine kinase was infected with pfu of HSV-1 strain McKrae by corneal scarification. (a) Images prior to infection showed infection-dependent firefly luciferase bioluminescence in the infected eye and periocular tissues (red arrow). (b) Luciferase activity in the ear (red arrow) was present constitutively on day 6. Adapted from K. E. Luker and G. D. Luker [43].
