Exercise Training, Lymphocyte Subsets and Their Cytokines Production: Experience of an Italian Professional Football Team and Their Impact on Allergy

Table 3

Cytokines producing lymphocytes, allergic and nonallergic subjects (percentage)∗.

	1st sample	𝑃^§ (1st-2nd)	2nd sample	𝑃^§ (2nd-3rd)	3rd sample	𝑃^§ (1st–3rd)
Allergic (7 subjects)
IL-2	20.80 (10.80–26.20)	0.063	12.16 (9.87–16.06)	0.028	17.25 (13.50–24.95)	0.463
TNF-𝛼	28.90 (16.50–36.60)	0.612	25.88 (20.01–33.11)	0.345	31.90 (24.38–35.10)	0.753
IFN-𝛾	14.40 (12.30–15.40)	0.091	12 (9.33–14.68)	0.028	15.30 (11.18–19.98)	0.500
IL-4	4.19 (2.60–7.20)	0.042	2.21 (1.58–3.32)	0.028	1.75 (1.38–2.08)	0.028
Nonallergic (18 subjects)
IL-2	22.95 (15.30–27.75)	0.003	10.98 (9.35–15.06)	0.006	16.20 (12.20–20.00)	0.019
TNF-𝛼	31.55 (26.98–41.38)	0.008	26.36 (18.55–31.06)	0.022	28.45 (22.55–32.18)	0.041
IFN-𝛾	11.55 (9.60–16.83)	0.754	13.06 (9.34–15.73)	0.109	13.70 (10.30–16.90)	0.423
IL-4	3.85 (3.04–5.65)	0.091	3.29 (2.82–3.82)	0.009	2.70 (2.03–3.43)	0.021

∗Data are expressed in medians (interquartile range).
§Wilcoxon Signed Ranks Test.