Protective Role of Omega-3 Polyunsaturated Fatty Acid against Lead Acetate-Induced Toxicity in Liver and Kidney of Female Rats

Table 2

The activities of AST, ALT, ALP, LDH, levels of MDA, total protein, albumin, urea, and creatinine after lead exposure and Omega-3 treatment in serum of female rats.

Parameters	Experimental groups
	(Group 1); −ve control	(Group 2); Omega-3; (125 mg/kg b.w.) + lead acetate	(Group 3); Omega-3; (260 mg/kg b.w.) + lead acetate	(Group 4); +ve control
AST (U/L)	56.69 ± 0.565^a	58.63 ± 1.279^a	51.35 ± 0.373^a	104.27 ± 0.677^b
ALT (U/L)	36.32 ± 0.276^a	40.53 ± 0.260^a	38.69 ± 0.416^a	90.07 ± 0.612^b
ALP (U/L)	42.43 ± 0.358^a	48.74 ± 0.475^a	41.44 ± 0.279^a	87.77 ± 0.534^b
LDH (U/L)	149.29 ± 0.703^a	159.07 ± 0.845^a	148.81 ± 0.845^a	219.88 ± 1.082^b
Total protein (gm/dL)	7.10 ± 0.115^a	6.11 ± 0.244^a	7.61 ± 0.217^a	4.88 ± 0.103^b
Albumin (g/dL)	3.96 ± 0.095^a	3.75 ± 0.071^a	4.05 ± 0.102^a	2.66 ± 0.083^b
Urea (mg/dL)	31.09 ± 0.225^a	40.04 ± 0.715^a	31.59 ± 0.450^a	63.56 ± 0.962^b
Creatinine (mg/dL)	0.38 ± 0.004^a	0.47 ± 0.011^a	0.38 ± 0.004^a	0.96 ± 0.026^b
MDA (nmol/mL)	17.08 ± 0.296^a	18.81 ± 0.538^a	17.47 ± 0.349^a	51.99 ± 0.620^b

Values are expressed as means ± SE; 𝑛=7 for each treatment group. a, b indicate the significant results statistically; 𝑃<0.05.