Protective Role of Omega-3 Polyunsaturated Fatty Acid against Lead Acetate-Induced Toxicity in Liver and Kidney of Female Rats

Table 3

The effect of Omega-3 and lead acetate on specific activity of liver and kidney antioxidant enzymes in female rats.

Parameters	Experimental groups
	(Group 1); −ve control	(Group 2); Omega-3; (125 mg/kg b.w.) + lead acetate	(Group 3); Omega-3; (260 mg/kg b.w.) + lead acetate	(Group 4); +ve control
Liver
GPX (U/mg protein)	40.53 ± 0.240^a	36.54 ± 0.909^a	48.50 ± 0.341^a	22.44 ± 0.487^b
CAT (U/mg protein)	27.53 ± 0.554^a	23.92 ± 0.583^a	34.46 ± 0.743^a	16.67 ± 0.489^b
SOD (U/mg protein)	11.34 ± 0.355^a	10.40 ± 0.346^a	18.11 ± 0.495^b	7.64 ± 0.303^c
GSH (U/g tissue)	27.84 ± 0.312^a	26.08 ± 0.446^a	29.16 ± 0.271^a	12.72 ± 0.303^b
MDA (nmol/g tissue)	50.34 ± 0.259^a	54.62 ± 0.288^a	51.41 ± 0.282^a	100.54 ± 0.322^b
Kidney
GPX (U/mg protein)	30.64 ± 0.521^a	27.43 ± 0.597^a	39.89 ± 0.479^b	21.54 ± 0.360^c
CAT (U/mg protein)	53.17 ± 0.477^a	46.97 ± 0.557^a	63.30 ± 0.583^b	20.41 ± 0.562^c
SOD (U/mg protein)	98.92 ± 0.457^a	81.99 ± 0.693^a	98.60 ± 0.285^a	41.75 ± 0.451^b
GSH (U/g tissue)	53.81 ± 0.682^a	50.39 ± 0.350^a	55.01 ± 0.724^a	28.51 ± 0.334^b
MDA (nmol/g tissue)	22.19 ± 0.320^a	37.60 ± 0.382^b	22.94 ± 0.515^a	51.82 ± 0.313^c

Values are expressed as means ± SE; 𝑛=7 for each treatment group. a, b, and c indicate the significant results statistically; 𝑃<0.05.