Effects of Single Pill-Based Combination Therapy of Amlodipine and Atorvastatin on Within-Visit Blood Pressure Variability and Parameters of Renal and Vascular Function in Hypertensive Patients with Chronic Kidney Disease

Table 1

Baseline characteristics.

Variables	Mean ± SD or %
Age (y)	67.7±12.4
Sex (male/female)	14/6
Body mass index (kg/m^2)	26.8±4.9
Alcohol (%)	40
Smoking (%)	20
Diabetes mellitus (%)	40
Dyslipidemia (%)	85
Previous cardiovascular disease (%)	20
Clinic blood pressure
SBP (mmHg)	151±15
DBP (mmHg)	81±8
Glucose-lipid metabolism
Fasting plasma glucose (mg/dL)	130±51
Glycated hemoglobin (%)	6.1±0.8
Total cholesterol (mg/dL)	230±33
LDL-cholesterol (mg/dL)	143±27
HDL-cholesterol (mg/dL)	63±21
Triglycerides (mg/dL)	195±140
Renal function
Serum creatinine (mg/dL)	1.04±0.44
eGFR (mL/min/1.73 m^2)	60.4±25.8
UACR (mg/g-Cr)	1034±1480
Serum cystatin C (mg/L)	1.30±0.45
Inflammatory and oxidative stress markers
hs-CRP (mg/dL)	0.18±0.24
Serum pentosidine (μg/mL)	0.036±0.013
Medication
Statin (%)	30
Calcium channel blockers (%)	100
RAS inhibitors (%)	85

Values are means ± SD. SBP: systolic blood pressure; DBP: diastolic blood pressure; eGFR: estimated glomerular filtration rate; UACR: urine albumin-to-creatinine ratio; CRP: C-reactive protein; RAS: renin-angiotensin system.