Research Article
Comparison of the Freiburg and Charlson Comorbidity Indices in Predicting Overall Survival in Elderly Patients with Newly Diagnosed Multiple Myeloma
Table 3
Prevalence of comorbidities according to the Charlson and Freiburg comorbidity indices and patient distribution according to comorbidity indices.
| (a) Prevalence of comorbidities according to the Charlson comorbidity index. |
| | Comorbidity | Yes | No |
| | Myocardial infarct | 7 (5.5%) | 120 (94.5%) | | Congestive heart failure | 7 (5.5%) | 120 (94.5%) | | Peripheral vascular disease | 0 (0%) | 127 (100%) | | Cerebrovascular disease | 6 (4.7%) | 121 (95.3%) | | Dementia | 0 (0%) | 127 (100%) | | Chronic lung disease | 14 (11.0%) | 113 (89.0%) | | Connective tissue disease | 2 (1.6%) | 125 (98.4%) | | Ulcer disease | 8 (6.3%) | 119 (93.7%) | | Mild liver disease | 2 (1.6%) | 125 (98.4%) | | DM | 24 (18.9%) | 103 (81.1%) | | Hemiplegia | 6 (4.7%) | 121 (95.3%) | | Moderate to severe renal disease | 1 (0.8%) | 126 (99.2%) | | DM with end organ damage | 0 (0%) | 127 (100%) | | Any tumor | 8 (6.3%) | 119 (93.7%) | | Leukemia | 0 (0%) | 127 (100%) | | Lymphoma | 0 (0%) | 127 (100%) | | Moderate to severe liver disease | 2 (1.6%) | 125 (98.4%) | | Metastatic solid tumor | 2 (1.6%) | 125 (98.4%) | | AIDS | 0 (0%) | 127 (100%) |
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DM, diabetes mellitus; AIDS, acquired immune deficiency syndrome.
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| (b) Prevalence of comorbidities according to the Freiburg comorbidity index. |
| | Component | Yes | No |
| Renal impairment
(eGFR ≤ 30 mL/min/1.73 m2) | 15 (11.8%) | 112 (88.2%) | | Performance status (KPS ≤ 70) | 52 (40.9%) | 74 (58.3%) | | Moderate or severe lung disease | 14 (11.0%) | 113 (89.0%) |
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eGFR, estimated glomerular filtration rate; KPS, Karnofsky performance status.
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| (c) Patient distribution according to comorbidity indices. |
| |
| (I) CCI total
(comorbidity scores without age points) | | | 0 | 65 (51.2%) | | 1 | 37 (29.1%) | | 2 | 12 (9.4%) | | 3 | 5 (3.9%) | | 4 | 6 (4.7%) | | 6 | 1 (0.8%) | | 8 | 1 (0.8%) | (II) CCI total
(comorbidity scores with age points) | | | 2 | 25 (19.7%) | | 3 | 49 (38.6%) | | 4 | 31 (24.4%) | | 5 | 9 (7.1%) | | 6 | 5 (3.9%) | | 7 | 6 (4.7%) | | 9 | 1 (0.8%) | | 13 | 1 (0.8%) | | (III) CCI score group (with age points) | | | Low (2-3) | 53 (41.7%) | | High (≥4) | 74 (58.3%) | | (IV) FCI | | | 0 | 59 (46.5%) | | 1 | 54 (425%) | | 2 | 12 (9.4%) | | 3 | 1 (0.8%) | | Unknown | 1 (0.8%) |
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CCI, Charlson comorbidity index; FCI, Freiburg comorbidity index.
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