RNA Sequencing Reveals Upregulation of RUNX1-RUNX1T1 Gene Signatures in Clear Cell Renal Cell Carcinoma

Table 2

Summary of selected genes of interest differentially expressed in ccRCC samples.

Symbol	Entr. ID	log2-fold change	𝑃 value	Notes
SLC6A3	6531	8.41	1.59𝐸−139
CA9	768	7.78	6.24𝐸−82	Hypoxia
FGG	2266	7.42	8.98𝐸−62
NDUFA4L2	56901	6.95	7.34𝐸−122
EGLN3	112399	5.89	7.19𝐸−97	Hypoxia
LOC100131551	100131551	4.38	1.18𝐸−42
C3	718	5.31	1.81𝐸−89
CYP2J2	1573	5.53	2.41𝐸−88
ANGPTL4	51129	5.63	3.39𝐸−87	Hypoxia
FCGR3A	2214	4.72	2.88𝐸−57
NETO2	81831	4.43	5.52𝐸−49	RUNX1
UBD	10537	4.33	1.21𝐸−59
CP	1356	4.47	1.80𝐸−67
PLIN2	123	4.12	3.01𝐸−53	Myc
PVT1	5820	3.79	6.24𝐸−56	Activator
ENO2	2026	3.19	2.19𝐸−21	Hypoxia
VEGF-A	7422	3.15	3.48𝐸−30	Hypoxia
SLC1A3	6507	3.04	8.64𝐸−24	RUNX1
PLK2	10769	2.82	2.57𝐸−22	RUNX1
GBP2	2634	2.62	1.37𝐸−24	RUNX1
VCAN	1462	2.44	4.65𝐸−24	RUNX1
COL1A1	1277	2.31	1.03𝐸−22	SWI/SNF
SEL1L3	23231	1.84	5.38𝐸−13	SWI/SNF
BCAT1	586	1.83	7.89𝐸−08	SWI/SNF
SIM2	6493	−5.70	2.02𝐸−53	TF
SLC13A3	64849	−5.97	4.53𝐸−52
SERPINA5	5104	−5.81	2.08𝐸−42
SFRP1	6422	−5.91	5.30𝐸−48	Wnt
KCNJ1	3758	−7.26	4.84𝐸−70	Kidney
SCNN1G	6340	−8.95	7.28𝐸−64
TFAP2B	7021	−7.64	5.21𝐸−44	TF
KNG1	3827	−8.97	4.07𝐸−91
SLC12A1	6557	−8.16	1.85𝐸−90	Kidney
HSFY2	159119	−7.41	4.54𝐸−42	TF
SLC22A8	9376	−8.10	1.94𝐸−64	Kidney
GP2	2813	−11.51	1.74𝐸−57
AQP2	359	−11.64	9.68𝐸−118	Kidney
UMOD	7369	−12.12	3.25𝐸−127	Kidney