Differential Expression of Osteo-Modulatory Molecules in Periodontal Ligament Stem Cells in Response to Modified Titanium Surfaces
Figure 5
Effect of NFAT inhibitor or -catenin knockdown on surface-dependent alkaline phosphatase (ALP) activity. (a) Cells were treated with the NFAT inhibitor VIVIT (500 nM) or (b) transfected with -catenin-specific siRNA, and ALP activity was assessed after 4 days of periodontal ligament stem cell culture. A representative result from three independent experiments is shown. versus control (tissue culture polystyrene); versus pretreatment (PT) substrate; versus sand-blasted, large-grit acid-etched substrate; , versus modified PT substrate.
