Computational Design of Apolipoprotein E4 Inhibitors for Alzheimer’s Disease Therapy from Traditional Chinese Medicine

Figure 7

RMSF values of ApoE4 with docked ligand or no ligand (Apo) (a) Solapalmitine, (b) Isodesacetyluvaricin, and (c) Budmunchiamine L5 with simulation times of 5000 ps; the no-ligand binding protein (d) was used as the control.