Anticancer Activities of Citrus Peel Polymethoxyflavones Related to Angiogenesis and Others

Figure 1

Polymethoxyflavones exert beneficial effects through antigrowth, antiangiogenesis and cell cycle arrest commands or mediate signals to live or die by apoptosis. At one level, this depiction is simplistic, as different cancer cells are exposed to a specific complex microenvironment, each of these pathways regulated by PMFs is connected with signals originating from other cells in the tumor microenvironment. Schematic representation of the main molecular mechanisms of flavonoids in citrus peel on anticancer.