Breast Cancer Prognosis Risk Estimation Using Integrated Gene Expression and Clinical Data

Table 5

Prognosis based classification results of the RAND and IPRE algorithms in the testing dataset of (a) the Desmedt and (b) the Vijver.

Algorithm		𝑁	TN	FP	TP	FN	SE (95% CI)	SP (95% CI)	ACC (95% CI)
(a) Desmedt dataset	RAND	190	128	24	23	15	0.605 (0.45 to 0.76)	0.842 (0.78 to 0.90)	0.795 (0.74 to 0.85)
	IPRE	190	133	19	23	15	0.605 (0.45 to 0.76)	0.875 (0.82 to 0.93)	0.821 (0.77 to 0.88)
(b) Vijver dataset	RAND	150	91	15	26	16	0.619 (0.47 to 0.77)	0.858 (0.79 to 0.92)	0.791 (0.73 to 0.86)
	IPRE	150	101	5	29	15	0.659 (0.52 to 0.80)	0.953 (0.91 to 0.99)	0.867 (0.81 to 0.92)