Antidiabetic Activity of Pterospermum acerifolium Flowers and Glucose Uptake Potential of Bioactive Fraction in L6 Muscle Cell Lines with Its HPLC Fingerprint
Table 4
Effect of ethyl acetate fraction and subfractions of flowers of Pterospermum acerifolium (L.) Willd on levels of serum liver enzymes.
Treatment
ALT (IU/L)
AST (IU/L)
ALP (IU/L)
Normal control
25.48 ± 0.337
32.14 ± 0.24
11.88 ± 0.24
Diabetic control
54.91 ± 0.45aaaa
72.35 ± 0.365aaaa
27.16 ± 0.041aaa
PAFEF1
44.07 ± 0.273
58.28 ± 0.348
22.39 ± 0.085
PAFEF2
41.60 ± 0.444
56.25 ± 0.387
21.33 ± 0.069
PAFE1-1
42.03 ± 0.711
53.48 ± 0.570
20.27 ± 0.064
PAFE1-2
40.94 ± 0.195
51.34 ± 0.364b
18.25 ± 0.054
PAFE2-1
38.75 ± 0.359bb
43.86 ± 0.770bb
17.21 ± 0.039
PAFE2-2
31.45 ± 0.371bbb
41.73 ± 0.484bbb
15.21 ± 0.053b
PAFE3-1
51.64 ± 0.478aaaa
69.76 ± 0.208aaaa
28.37 ± 0.073aaaa
PAFE3-2
49.77 ± 0.201aaa
68.90 ± 0.612aaa
27.32 ± 0.033aaa
STD drug
28.78 ± 0.251bbbb
37.17 ± 0.306bbbb
14.50 ± 0.064bb
The results are expressed as mean ± standard error of the mean (SEM). Probability values of < 0.0001, aaa < 0.001, aa < 0.01, and a < 0.05 were compared with normal control. Probability values of bbbb < 0.0001, bbb < 0.001, bb < 0.01, and b < 0.05 were compared with disease control.