BioMed Research International / 2014 / Article / Tab 2

Research Article

In Vitro Antioxidant, Antibacterial, and Cytotoxic Activity and In Vivo Effect of Syngonium podophyllum and Eichhornia crassipes Leaf Extracts on Isoniazid Induced Oxidative Stress and Hepatic Markers

Table 2

Effect of S. podophyllum and E. crassipes leaf aqueous extracts on isoniazid induced alterations of serum markers in Wistar rats.

ParametersControlINHINH + L52INH + SPINH + EC

CRE mg/dL0.353 ± 0.111.830 ± 0.06***0.550 ± 0.19#1.800 ± 0.06***0.223 ± 0.10#
BIL total mg/dL0.247 ± 0.06 0.580 ± 0.05**0.300 ± 0.07#0.660 ± 0.10**0.417 ± 0.14#
BIL direct mg/dL0.113 ± 0.030.297 ± 0.06*0.153 ± 0.03#0.433 ± 0.10***0.223 ± 0.10#
ALP U/L29.85 ± 7.90220.64 ± 45.39***47.63 ± 10.37#246.25 ± 47.19***88.57 ± 23.59#
SGOT U/L40.66 ± 11.55174.95 ± 19.80***50.45 ± 4.37#184.74 ± 19.10***131.78 ± 18.57#
SGPT U/L38.73 ± 6.91138.24 ± 10.96***49.67 ± 5.74#148.43 ± 10.94***76.24 ± 10.68**
Hb mg/dL13.35 ± 0.6610.96 ± 1.86#12.21 ± 1.33***6.88 ± 0.38#11.78 ± 0.25#

Data represent mean ± SD of three replicates ( ). One-way ANOVA followed by Dunnett’s Multiple Comparison Test was used to compare control group from other experimental groups (# , , , and ). INH: isoniazid, L52: Liv52, SP: Syngonium podophyllum, EC: Eichhornia crassipes, CRE: creatinine, BIL: bilirubin, ALP: alkaline phosphatase, SGOT: serum glutamic oxaloacetic transaminase, SGPT: serum glutamate pyruvate transaminase, and Hb: haemoglobin.