Increased Release Time of Antibiotics from Bone Allografts through a Novel Biodegradable Coating

Figure 1

Antibiotic coating methods. As a first step, 50 mg bone allografts were incubated in a 10 mg/mL antibiotic solution for 24 hours. The Chi used for coating was 2 weight %; the alginate was 4 weight %. The final step in each method was lyophilization or drying in an oven resulting in a dry bone allograft which looks the same to the naked eye as a regular uncoated graft.