Expression and Clinical Significance of the Autophagy Proteins BECLIN 1 and LC3 in Ovarian Cancer

Table 2

Correlation of BECLIN 1 positivity (in terms of H ≥ 40) with clinical-pathological characteristics. (a) Statistical correlation with histologic grade; (b) statistical correlation with pathologic stage at diagnosis.

(a)

Grade	I-II	III	Number of cases
BECLIN 1
+	21	20	41
−	2	18	20
Total	23	38	61

Chi-square = 8.05
DF = 1
P = 0.0046
Fischer’s test P = 0.002.

(b)

Stage	I-II	III-IV	Number of cases
BECLIN 1
+	24	17	41
−	10	10	20
Total	34	27	61

Chi-square = 0.13
DF = 1
P = 0.7
Fischer’s test P = 0.59.