Research Article
Prophylactic Efficacy of Melatonin on Cyclophosphamide-Induced Liver Toxicity in Mice
Table 1
Effects of pretreatment with different doses of melatonin on serum toxicity marker enzymes along with CP administration.
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CP: cyclophosphamide; ALP: alkaline phosphatase; ALT: alanine transaminase; AST: aspartate transaminase. aValues are the mean ± standard deviation for each group of 5 mice. bP < 0.001 compared to the control; cno significant difference compared to the control group; dP < 0.01 compared with the CP-treated group; eP < 0.001 compared with the CP-treated group; fP < 0.05 compared with the CP-treated group. The data were analyzed with one-way ANOVA and Tukey's HSD test. |