Specific Growth Rate Determines the Sensitivity of Escherichia coli to Lactic Acid Stress: Implications for Predictive Microbiology
Figure 1
Sensitivity to lactic acid stress (150 mM HLac, pH = 4.6, 10.3% NaCl) at 27°C of E. coli 683 harvested at three different specific growth rates from (a) batch or (b) chemostat cultures at 37°C in TSB. Sensitivity was determined as CFU/CFU at time zero. GR = growth rate at harvest. Symbols indicate the mean of three replicates and error bars at the 95% confidence interval.
