Research Article

Computational Study to Determine When to Initiate and Alternate Therapy in HIV Infection

Table 3

Monte Carlo simulation outcome for SVF and SWATCH strategies.
(a) SVF

(years) (years)

0.5 14.01 ± 4.34 298
1 13.93 ± 4.39 292
1.5 13.82 ± 4.43 284
2 13.61 ± 4.38 277
3*13.06 ± 4.08 259
4*12.83 ± 4.55 253

(b) SWATCH

(years) (years)

0.5 15.54 ± 4.79 466
1 15.45 ± 4.81 454
1.5 15.13 ± 4.79 442
2* 14.69 ± 4.68 427
3* 13.67 ± 4.38 386
4* 12.59 ± 3.84 336

is the average year when immunological failure occurs for the 1000 random samples and the respective standard deviation . is the number of cases that do not experience immunological failure after 30 years postinfection. *Star represents a statistically significant difference with respect to the group of years ( ). There is a significant difference between SWATCH and SVF for all the groups when .