Table 3: Global-brain volumetric measurements in total group of patients with ALS and normal controls by SIENAX.

NCALS

BPF 0.0090.000
NCV (mm3) 0.0010.000
NGMV (mm3) 0.0160.004
NWMV (mm3) 0.0060.004

BPF: brain parenchyma fraction; NCV: normalized neocortex volume; NGMV: normalized gray matter volume; NWMV: normalized white matter volume.
: P value in total group analysis between patients with ALS and normal controls, by using two-sample -test.
: P value in total group analysis between patients with ALS and normal controls, by using analysis of covariance, with age as covariate.