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BioMed Research International
Volume 2014, Article ID 473419, 7 pages
Research Article

Complications of Trauma Patients Admitted to the ICU in Level I Academic Trauma Centers in the United States

1Department of Neurosciences, University of Messina, Via Consolare Valeria, 98125 Messina, Italy
2Department of Biostatistics, College of Public Health and Health Professions, College of Medicine, University of Florida, P.O. Box 117450, 2004 Mowry Road, 5th Floor CTRB, Gainesville, FL 32611-7450, USA
3Department of Clinical and Experimental Medicine and Pharmacology, University of Messina, Via Consolare Valeria, 98125 Messina, Italy
4Department of Human Pathology, University of Messina, Via Consolare Valeria, 98125 Messina, Italy
5University of South Florida and Trauma Services, Ocala Regional Medical Center, Ocala, FL, USA

Received 16 February 2014; Revised 22 May 2014; Accepted 22 May 2014; Published 3 June 2014

Academic Editor: Markus Kipp

Copyright © 2014 Stefania Mondello et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. The aims of this study were to evaluate the complications that occur after trauma and the characteristics of individuals who develop complications, to identify potential risk factors that increase their incidence, and finally to investigate the relationship between complications and mortality. Methods. We did a population-based retrospective study of trauma patients admitted to ICUs of a level I trauma center. Logistic regression analyses were performed to determine independent predictors for complications. Results. Of the 11,064 patients studied, 3,451 trauma patients developed complications (31.2%). Complications occurred significantly more in younger male patients. Length of stay was correlated with the number of complications . The overall death rate did not differ between patients with or without complications. The adjusted odds ratio (OR) of developing complication for patients over age 75 versus young adults was 0.7 . Among males, traumatic central nervous system (CNS) injury was an important predictor for complications (adjusted OR 1.24). Conclusions. Complications after trauma were found to be associated with age, gender, and traumatic CNS injury. Although these are not modifiable factors, they may identify subjects at high risk for the development of complications, allowing for preemptive strategies for prevention.