Age Modulates Fe3O4 Nanoparticles Liver Toxicity: Dose-Dependent Decrease in Mitochondrial Respiratory Chain Complexes Activities and Coupling in Middle-Aged as Compared to Young Rats
Figure 2
Effects of iron oxide nanoparticles () on young liver mitochondrial respiratory chain complexes activities. (a) reflects complexes I, III, and IV activities and is measured using glutamate and malate. (b) reflects complexes II, III, and IV activities and is measured using succinate. (c) reflects complex IV activity and is measured using TMPD and ascorbate as mitochondrial substrates. Data are means ± SEM
