Research Article

Antiproliferative and Apoptotic Effects of Sesbania grandiflora Leaves in Human Cancer Cells

Figure 2

Nuclear staining using DAPI of human lung cancer cells A549 in the presence or absence of the methanolic fraction of S. grandiflora leaves. (a) Untreated A549 cells. (b) A549 cells treated with IC50 dose of the methanolic fraction for 24 h. Arrows indicate cell shrinkage, nuclear fragmentation, and margination of the nucleus, all associated with the apoptotic mode of cell death. (c) Quantitative results for the number of apoptotic cells per 100 cells in total. Magnification 200x.
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