Extracts from Vatica diospyroides Type SS Fruit Show Low Dose Activity against MDA-MB-468 Breast Cancer Cell-Line via Apoptotic Action
Figure 2
Effect of V. diospyroides type SS fruit on expression of the tumor suppressor protein p53 and proapoptotic protein, namely, the Bax. (a-b) MDA-MB-468 cells were treated with the extract of fruit pericarp, whereas (c-d) the cells were treated with the extract of fruit cotyledon, all at concentration of half IC50. The cellular proteins were separated on SDS-polyacrylamide gels and subsequently transferred to membranes. The protein levels were determined by western blots with appropriate antibodies directed against each protein.
