Preliminary In Vitro and In Vivo Evaluation of Antidiabetic Activity of Ducrosia anethifolia Boiss. and Its Linear Furanocoumarins

Table 2

Effect of Ducrosia anethifolia total extract on blood glucose level and liver injury biomarkers in STZ-induced diabetes in rats.

Parameter	Normal control	D. anethifolia treated normal	STZ treated	STZ + D. anethifolia treated	STZ + glibenclamide
Blood glucose level	111.53±3.33^a	116.58±4.00^a	365.00±23.20^b	165.60±8.30^d	151.50±2.10^c
AST	2.55±0.19^a	2.43±0.20^a	8.15±0.18^b	3.20±0.21^a	2.85±0.05^a
ALT	1.62±0.028^a	1.52±0.09^a	5.92±0.17^b	2.10±0.23^c	2.00±0.16^c
ALP	3.46±0.08^a	3.61±0.06^a	10.90±0.19^b	5.00±0.13^a	4.03±0.38^a
Total protein	117.47±16.00^a	119.90±9.22^a	65.48±6.49^b	100.70±9.21^a	107.00±2.64^a

Data are means ± SD of ten rats in each group. Liver injury biomarkers activities are expressed in 𝜇mol/mL (unit/mL).
Total protein is expressed in mg/mL. Statistical analysis is carried out using CoStat Computer Program coupled with post hoc (least significance difference LSD. The different groups were compared with each other at the same time and the unshared letter is significantly different at 𝑃≤0.05.