Preliminary In Vitro and In Vivo Evaluation of Antidiabetic Activity of Ducrosia anethifolia Boiss. and Its Linear Furanocoumarins

Table 5

Effect of Ducrosia anethifolia total extract on some glucolytic and gluconeogenic enzymes in STZ-induced diabetes in rats.

Groups	Parameters
	Normal control	D. anethifolia treated normal	STZ treated	STZ + D. anethifolia treated	STZ + Glibenclamide
HK	105.12±1.67^a	102.00±9.00^a	35.19±7.60^b	57.18±0.95^c	76.99±8.89^d
PK	62.60±2.45^a	64.69±3.41^a	23.40±5.17^b	47.47±2.03^c	50.16±9.05^d
LDH	39.27±9.80^a	39.00±5.52^a	18.41±2.62^b	29.90±5.90^c	31.40±8.48^d
PEPCK	3.40±0.30^a	3.76±0.45^a	1.16±0.20^b	2.58±0.23^c	2.87±0.28^d

Data are means ± SD of ten rats in each group. Blood glucose level is expressed in mg/dL. PK, HK, LDH and PEPCK are expressed in 𝜇mol/mg protein/min. Statistical analysis is carried out using Co stat Computer Program coupled with post-hoc (least significance difference LSD. The different groups were compared with each other at the same times and the unshared letter is significant difference at 𝑃≤0.05.