Antisecretory Effect of Hydrogen Sulfide on Gastric Acid Secretion and the Involvement of Nitric Oxide

Figure 3

Effect of NaHS treatment on luminal level of nitric oxide. The luminal content of NO was significantly increased by NaHS. C: control, NaHS: animals received NaHS (80 μg/kg, i.v.) just prior to stimulation of the gastric acid secretion, NaHS + L-NAME: animals received L-NAME at 10 mg/kg, i.v., 5 min before the administration of NaHS (80 μg/kg, i.v.), PAG: rats received cystathionine-γ-lyase inhibitor, propargylglycine (PAG), at 50 mg/kg, i.v. concomitant with the gastric distention. ^∗𝑃<0.01 versus the control group; 𝛽 in the above column indicates a significant decrease (^𝛽𝑃<0.01) as compared to the control. Data are expressed as mean ± S.E.M.