Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy
Figure 2
Electron microscopy showing (a) a normal glomerulus (E: endothelial cell; P: podocytes; Lumen: capillary lumen); and (b) transplant glomerulopathy with presence of a well-developed basement membrane (BM) along the entire capillary circumference, mesangial expansion (M), and accumulation of subendothelial deposit (D) (magnification ×7000) (source: Northern General Hospital, Sheffield).