BioMed Research International / 2014 / Article / Fig 1

Research Article

Consumption of Green Coffee Reduces Blood Pressure and Body Composition by Influencing 11β-HSD1 Enzyme Activity in Healthy Individuals: A Pilot Crossover Study Using Green and Black Coffee

Figure 1

Inhibition of glucose-6-phosphate by chlorogenic acid. CGA is involved in blocking the uptake of glucose-6-phosphate by inhibiting glucose-6-phosphate translocase. This prevents the enzyme glucose-6-phosphate dehydrogenase from providing NADPH as a cofactor for the reductase activity and so the conversion of cortisone to cortisol is inhibited. NADPH: nicotinamide adenine dinucleotide phosphate. Adapted from a Ph.D. thesis by Al Moosawi, Queen Margaret University, 2010 [42].

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