BioMed Research International / 2014 / Article / Fig 2

Research Article

Resveratrol Ameliorates Motor Neuron Degeneration and Improves Survival in SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

Figure 2

Resveratrol administration prevented motor neuron death in mice at the age of 120 days. (a) Immunofluorescent staining of motor neurons (white arrows) with SMI-32 (green) antibody in the anterior horn of spinal cord from different groups of mice. (b) Photomicrographs of Nissl’s stained-motor neurons (black arrows) in the anterior horn of the spinal cord of mice in different groups. (A) WT-Veh group, (B) WT-RSV group, (C) Tg-Veh group, and (D) Tg-RSV group. (c) Quantification of motor neurons in the anterior horn of lumbar spinal cord in different groups. The values are means ± SEM. versus WT-Veh group; versus Tg-Veh group; versus Tg-RSV group. in each group. Scale bar = 100 μm.

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