BioMed Research International / 2014 / Article / Fig 4

Research Article

Resveratrol Ameliorates Motor Neuron Degeneration and Improves Survival in SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

Figure 4

Effects of resveratrol on oxidative capacity in different groups of mice. (a) Western blot assay of Sirt1 and PGC1-α in the spinal cord tissues of WT and transgenic mice treated or untreated with resveratrol. (b) Relative Sirt1 mRNA expression in the spinal cords of different groups of mice. (c-d) Quantitative analysis of the protein expression of (c) SIRT1 and (d) PGC1-α in the spinal cords. (e-f) MDA concentration in (e) serum and (f) spinal cords from different groups of mice. The values are means ± SEM. and versus WT-Veh group; and versus Tg-Veh group; and versus Tg-RSV group. in each group.

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