The Role of M1 and M2 Macrophages in Prostate Cancer in relation to Extracapsular Tumor Extension and Biochemical Recurrence after Radical Prostatectomy
Table 3
Univariate (Pearson test, Mann Whitney Test, and -test) and multivariate (Cox proportional hazard model) analysis of common variables to predict BCR.
Variables
Univariate analysis value
Multivariate analysis
value
Risk ratio
95% CI
Preoperative PSA
Ns
—
Biopsy GS > 7
0.0009
0.07
2.26
1.1–10.47
Anatomopathological GS > 7
0.0006
0.02
16.04
1.44–177.9
Pathological stage
0.0147
0.03
3.43
1.09–11.8
Lymphnode invasion
Ns
—
Status
Ns
—
Surgical margin status
Ns
—
High density of macrophages M1 and M2 in three hot spots (above median value)
