Thai Massage, and Thai Herbal Compress versus Oral Ibuprofen in Symptomatic Treatment of Osteoarthritis of the Knee: A Randomized Controlled Trial
Table 4
Mean values of VAS assessing stiffness, Lequesne’s functional index, and time for climbing up ten steps in intent-to-treat patients ().
Variable
Treatment group
Week 0
Week 1
Week 2
Week 3
VAS assessing stiffness (mm)
Morning stiffness
TM
59.15 ± 22.88
41.90 ± 22.63***
29.00 ± 20.89***
16.65 ± 16.68***
THC
51.30 ± 30.89
34.40 ± 21.26**
16.80 ± 14.24***
5.05 ± 6.30***
Ibuprofen
54.00 ± 23.79
33.10 ± 21.67**
23.25 ± 20.44***
15.60 ± 19.56***
Stiffness after rest
TM
53.80 ± 22.16
36.85 ± 20.58***
23.60 ± 17.97***
19.95 ± 19.04***
THC
49.80 ± 26.86
30.70 ± 22.29***
17.85 ± 14.50***
10.65 ± 12.49***
Ibuprofen
53.10 ± 24.17
34.70 ± 19.16**
24.10 ± 20.76***
16.30 ± 18.28***
Total stiffnessa
TM
112.95 ± 41.04
78.75 ± 38.88***
52.60 ± 36.50***
36.60 ± 32.22***
THC
101.10 ± 55.42
65.10 ± 41.00***
34.65 ± 28.35***
15.70 ± 15.85***
Ibuprofen
107.10 ± 44.75
67.80 ± 37.47**
47.35 ± 38.82***
31.90 ± 36.28***
Lequesne’s functional index (score)
TM
13.50 ± 2.38
11.18 ± 3.13***
9.40 ± 3.23***
7.73 ± 3.30***
THC
13.25 ± 4.07
10.68 ± 3.54**
8.30 ± 2.93***
6.53 ± 3.73***
Ibuprofen
12.70 ± 2.41
10.20 ± 2.59***
8.35 ± 3.05***
7.85 ± 3.31***
Time for climbing up ten steps (second)
TM
11.80 ± 4.26
10.50 ± 3.87*
9.10 ± 3.24**
8.25 ± 3.08***
THC
13.55 ± 5.61
10.70 ± 6.34*
8.90 ± 3.24***
7.95 ± 2.78***
Ibuprofen
13.15 ± 6.57
11.55 ± 6.23**
10.00 ± 4.41**
9.25 ± 3.61***
Data represent mean ± SD. aSummation of VAS that assessed morning stiffness and stiffness after rest. *P < 0.05, **P < 0.01, ***P < 0.001 versus baseline.
