BioMed Research International / 2014 / Article / Tab 1

Research Article

Modulation of TLR 3, 7 and 8 Expressions in HCV Genotype 3 Infected Individuals: Potential Correlations of Pathogenesis and Spontaneous Clearance

Table 1

Baseline characteristics of patients enrolled in this study.

ControlHCV infected (treatment naïve)Recombinant IFN treatedSpontaneous
clearance
RelapsedCirrhosis of liver

Number of patientsn = 20n = 20n = 20n = 20n = 20n = 20
Mean age (range), years46 (30–62)48 (31–64)31 (31–54)28 (20–48)47 (30–60)52 (33–68)
Gender (male : female)10 : 1015 : 0514 : 0614 : 0618 : 0215 : 05
Median BMI (range), kg/m226 (21–32)24 (30–38)26 (21–32)30 (21–39)25.5 (20–38)26 (31–35)
ALT!  ± SD (IU/L)37.42 ± 6.8156 ± 6.3121 ± 3.685 ± 5.8126 ± 2.3140 ± 8.5
AST#  ± SD (IU/L)34.65 ± 14.22118 ± 5.5156 ± 3.0 114 ± .3125.23 ± 2.6156 ± 4.3
Median HCV RNA levels at baseline (  IU/ml)425 (10–6500)25 (25–650)BDL1560 (107–20000)3265 (129–2000)

Alanine aminotransferase level shown in IU/L with its standard deviations.
#Alanine aspartate aminotransferase level shown in IU/L with its standard deviations.
All enzymatic methods were done at 37°C, in a Beckman Coulter Synchron CX5 PRO, USA, instrument.
SD: standard deviation, BMI: basal metabolic index, and BDL: below detection limit.