Research Article

The Long-Term Prognostic Significance of 6-Minute Walk Test Distance in Patients with Chronic Heart Failure

Table 1

Baseline characteristics of patients mean (SD) divided by survival to >5 years.

VariablesDead Alive value

Age (years)74.1 (8.9)67.9 (10.6)<0.0001
Males (%) 73750.184
BMI (kg·m−2)27.7 (5.7)28.9 (5.6)<0.0001
NYHA class <0.0001
 I/II3664
 III/IV5842
LVEF (%)33 (10)36 (9)<0.0001
FEV1/FVC (%)66 (16)70 (16)<0.0001
Resting HR (beats·min−1)76 (18)74 (20)0.165
Resting systolic BP (mmHg)132 (26)133 (24)0.158
Resting diastolic BP (mmHg)74 (14)78 (14)<0.0001
QRS duration (ms)121 (32)112 (29)<0.0001
Haemoglobin (g·dL−1)13.0 (1.7)13.9 (1.5)<0.0001
Log NT pro-BNP*7.7 (1.2)6.7 (1.3)<0.0001
Sodium (mmol·L−1)139 (4)139 (3)0.652
Potassium (mmol·L−1)4.4 (0.5)4.4 (0.5)0.777
Urea (mmol·L−1)9.3 (4.7)7.1 (3.6)<0.0001
Creatinine (u·moL−1)130 (51)110 (55)<0.0001
Diuretic (%)83840.760
ACE-inhibitor (%)78770.348
Beta-blocker (%)73690.322
Spironolactone (%)22200.202
6-MWT (m) 163 (153)269 (160)<0.0001

NYHA: New York Heart Association; BMI: body mass index; LVI: left ventricular impairment; LVEF*: left ventricular ejection fraction available in 67% of patients; 6-MWT: 6-min walk test; BP: blood pressure; log NT pro-BNP (pg·mL−1)* available in 92% of patients.