Acute Superoxide Radical Scavenging Reduces Blood Pressure but Does Not Influence Kidney Function in Hypertensive Rats with Postischemic Kidney Injury
Figure 5
(a) Normal appearance of glomeruli, interstitium, tubules, and blood vessels in SHAM operated animals. Very rare PAS positive casts in the lumen of the tubules. (b) Massive corticomedullary tubular necrosis (solid arrow). Intensive interstitial edema. Numerous PAS positive casts in the collecting ducts and dilatation of certain segments (dash arrow) of the proximal and distal tubules (with or without loss of brush border) in AKI control group. (c) AKI + TEMPOL group. Noticeable tubular dilatation. Slightly reduced tubular necrosis in the corticomedullary zone, with interstitial edema. Tubular casts in the renal medulla is comparable to AKI control animals.
