Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 512834, 6 pages
http://dx.doi.org/10.1155/2014/512834
Research Article

Watermelon (Citrullus lanatus (Thunb.) Matsum. and Nakai) Juice Modulates Oxidative Damage Induced by Low Dose X-Ray in Mice

1Department of Medical Laboratory Technology, Faculty of Health Sciences, Universiti Teknologi MARA, UiTM Puncak Alam, 42300 Bandar Puncak Alam, Selangor, Malaysia
2Department of Medical Imaging, Faculty of Health Sciences, Universiti Teknologi MARA, UiTM Puncak Alam, 42300 Bandar Puncak Alam, Selangor, Selangor, Malaysia

Received 20 February 2014; Revised 8 April 2014; Accepted 8 April 2014; Published 29 April 2014

Academic Editor: José Carlos Tavares Carvalho

Copyright © 2014 Mohd Khairul Amran Mohammad et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. O. Asita and T. Molise, “Antimutagenic effects of red apple and watermelon juices on cyclophosphamide-induced genotoxicity in mice,” African Journal of Biotechnology, vol. 10, no. 77, pp. 17763–17768, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Valko, D. Leibfritz, J. Moncol, M. T. D. Cronin, M. Mazur, and J. Telser, “Free radicals and antioxidants in normal physiological functions and human disease,” International Journal of Biochemistry and Cell Biology, vol. 39, no. 1, pp. 44–84, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Valko, C. J. Rhodes, J. Moncol, M. Izakovic, and M. Mazur, “Free radicals, metals and antioxidants in oxidative stress-induced cancer,” Chemico-Biological Interactions, vol. 160, no. 1, pp. 1–40, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. J. G. Scandalios, “Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses,” Brazilian Journal of Medical and Biological Research, vol. 38, no. 7, pp. 995–1014, 2005. View at Google Scholar · View at Scopus
  5. M. Srinivasan, N. Devipriya, K. B. Kalpana, and V. P. Menon, “Lycopene: an antioxidant and radioprotector against γ-radiation-induced cellular damages in cultured human lymphocytes,” Toxicology, vol. 262, no. 1, pp. 43–49, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Georgieva, B. Popov, and G. Bonev, “Radioprotective effect of Haberlea rhodopensis (Friv.) leaf extract on gamma-radiation-induced DNA damage, lipid peroxidation and antioxidant levels in rabbit blood,” Indian Journal of Experimental Biology, vol. 51, no. 1, pp. 29–36, 2013. View at Google Scholar
  7. C. L. Bladen, D. J. Kozlowski, and W. S. Dynan, “Effects of low-dose ionizing radiation and menadione, an inducer of oxidative stress, alone and in combination in a vertebrate embryo model,” Radiation Research, vol. 178, no. 5, pp. 499–503, 2012. View at Google Scholar
  8. S. S. Puthran, K. Sudha, G. M. Rao, and B. V. Shetty, “Oxidative stress and low dose ionizing radiation,” Indian Journal of Physiology and Pharmacology, vol. 53, no. 2, pp. 181–184, 2009. View at Google Scholar · View at Scopus
  9. K. S. Azab, M. Bashandy, M. Salem, O. Ahmed, Z. Tawfik, and H. Helal, “Royal jelly modulates oxidative stress and tissue injury in gamma irradiated male Wister Albino rats,” North American Journal of Medical Sciences, vol. 3, no. 6, pp. 268–276, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. T. P. A. Devasagayam, K. K. Boloor, and T. Ramasarma, “Methods for estimating lipid peroxidation: an analysis of merits and demerits,” Indian Journal of Biochemistry and Biophysics, vol. 40, no. 5, pp. 300–308, 2003. View at Google Scholar · View at Scopus
  11. T. P. A. Devasagayam, J. C. Tilak, K. K. Boloor, K. S. Sane, S. S. Ghaskadbi, and R. D. Lele, “Free radicals and antioxidants in human health: current status and future prospects,” Journal of Association of Physicians of India, vol. 52, pp. 794–804, 2004. View at Google Scholar · View at Scopus
  12. J. F. Kergonou, P. Bernard, M. Braquet, and G. Rocquet, “Effect of whole-body gamma irradiation on lipid peroxidation in rat tissues,” Biochimie, vol. 63, no. 6, pp. 555–559, 1981. View at Google Scholar · View at Scopus
  13. L. M. Martin, B. Marples, M. Coffey et al., “DNA mismatch repair and the DNA damage response to ionizing radiation: making sense of apparently conflicting data,” Cancer Treatment Reviews, vol. 36, no. 7, pp. 518–527, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Dizdaroglu, “Oxidatively induced DNA damage: mechanisms, repair and disease,” Cancer Letters, vol. 327, no. 1-2, pp. 26–47, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. P. M. Hanson, R. Yang, J. Wu et al., “Variation for antioxidant activity and antioxidants in tomato,” Journal of the American Society for Horticultural Science, vol. 129, no. 5, pp. 704–711, 2004. View at Google Scholar · View at Scopus
  16. M. Srinivasan, A. R. Sudheer, K. R. Pillai, P. R. Kumar, P. R. Sudhakaran, and V. P. Menon, “Lycopene as a natural protector against γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes in vitro,” Biochimica et Biophysica Acta—General Subjects, vol. 1770, no. 4, pp. 659–665, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. H. F. Waer and F. M. Shalaby, “Structural studies on the radio-protective effect of lycopene (tomato supplementation) against hepatic cellular injury induced by chronic doses of gamma radiation,” Journal of Cytology and Histology, vol. 3, article 145, 2012. View at Google Scholar
  18. D. Meydan, B. Gursel, B. Bilgici, B. Can, and N. Ozbek, “Protective effect of lycopene against radiation-induced hepatic toxicity in rats,” Journal of International Medical Research, vol. 39, no. 4, pp. 1239–1252, 2011. View at Google Scholar · View at Scopus
  19. M. I. Mohamed, M. K. A. Mohammad, A. M. Zakaria et al., “Induction of oxidative stress following low dose ionizing radiation in ICR mice,” World Journal of Medical Sciences, vol. 10, no. 2, pp. 198–203, 2014. View at Google Scholar
  20. A. V. Rao and L. G. Rao, “Carotenoids and human health,” Pharmacological Research, vol. 55, no. 3, pp. 207–216, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. M. P. Pinto, C. N. dos Santos, C. Henriquesa, G. Lima, and F. Quedas, “Lycopene content and antioxidant capacity of Portuguese watermelon fruits,” Electronic Journal of Environmental, Agricultural and Food Chemistry, vol. 10, no. 4, pp. 2090–2097, 2011. View at Google Scholar · View at Scopus
  22. K. Wasylikowa and M. van der Veen, “An archaeobotanical contribution to the history of watermelon, Citrullus lanatus (Thunb.) Matsum. & Nakai (syn. C. vulgaris Schrad.),” Vegetation History and Archaeobotany, vol. 13, no. 4, pp. 213–217, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Altaş, G. Kızıl, M. Kızıl, A. Ketani, and P. I. Haris, “Protective effect of Diyarbakır watermelon juice on carbon tetrachloride-induced toxicity in rats,” Food and Chemical Toxicology, vol. 49, no. 9, pp. 2433–2438, 2011. View at Google Scholar
  24. L. J. Marnett, “Oxy radicals, lipid peroxidation and DNA damage,” Toxicology, vol. 181-182, pp. 219–222, 2002. View at Publisher · View at Google Scholar · View at Scopus
  25. D. M. Wilson and D. Barsky, “The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA,” Mutation Research—DNA Repair, vol. 485, no. 4, pp. 283–307, 2001. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Shokrzadeh, A. Chabra, F. Naghshvar, and A. Ahmadi, “The mitigating effect of Citrullus colocynthis (L.) fruit extract against genotoxicity induced by cyclophosphamide in mice bone marrow cells,” The Scientific World Journal, vol. 2013, Article ID 980480, 8 pages, 2013. View at Publisher · View at Google Scholar
  27. M. P. Tarazona-Díaz, J. Viegas, M. Moldao-Martins, and E. Aguayo, “Bioactive compounds from flesh and by-product of fresh-cut watermelon cultivars,” Journal of the Science of Food and Agriculture, vol. 91, no. 5, pp. 805–812, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Perkins-Veazie, J. K. Collins, S. D. Pair, and W. Roberts, “Lycopene content differs among red-fleshed watermelon cultivars,” Journal of the Science of Food and Agriculture, vol. 81, no. 10, pp. 983–987, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. H. N. Saada, R. G. Rezk, and N. A. Eltahawy, “Lycopene protects the structure of the small intestine against gamma-radiation-induced oxidative stress,” Phytotherapy Research, vol. 24, supplement 2, pp. S204–S208, 2010. View at Publisher · View at Google Scholar · View at Scopus