Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 514948, 7 pages
Research Article

Relationship between Spectral-Domain Optical Coherence Tomography and Standard Automated Perimetry in Healthy and Glaucoma Patients

1Ophthalmology Department, Miguel Servet University Hospital, Aragon Health Sciences Institute, Isabel la Catolica 1-3, 50009 Zaragoza, Spain
2Department of Surgery, Gynecology and Obstetrics, University of Zaragoza, 50009 Zaragoza, Spain
3Department of Ophthalmology, University of Siena, 53100 Siena, Italy
4Department of Neurosciences, University of Pisa, 56126 Pisa, Italy

Received 28 February 2014; Revised 4 May 2014; Accepted 30 May 2014; Published 16 June 2014

Academic Editor: María Dolores Pinazo-Duran

Copyright © 2014 Beatriz Abadia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To evaluate the relationship between spectral-domain optical coherence tomography (OCT) and standard automated perimetry (SAP) in healthy and glaucoma individuals. Methods. The sample comprised 338 individuals divided into 2 groups according to intraocular pressure and visual field outcomes. All participants underwent a reliable SAP and imaging of the optic nerve head with the Cirrus OCT. Pearson correlations were calculated between threshold sensitivity values of SAP (converted to linear scale) and OCT parameters. Results. Mean age did not differ between the control and glaucoma groups (59.55 ± 9.7 years and 61.05 ± 9.4 years, resp.; ). Significant differences were found for the threshold sensitivities at each of the 52 points evaluated with SAP ( ) and the peripapillary retinal nerve fiber layer (RNFL) thicknesses, except at 3 and 9 clock-hour positions between both groups. Mild to moderate correlations (ranging between 0.286 and 0.593; ) were observed between SAP and most OCT parameters in the glaucoma group. The strongest correlations were found between the inferior RNFL thickness and the superior hemifield points. The healthy group showed lower and weaker correlations than the glaucoma group. Conclusions. Peripapillary RNFL thickness measured with Cirrus OCT showed mild to moderate correlations with SAP in glaucoma patients.