Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors

<table>Solvent accessible surface of hCA II in its complex with<b> 14</b>. The two molecules of the inhibitor bound within the active site cavity and on the protein surface are shown in stick representation. The hydrophobic cleft defined by residues Phe131, Val135, Pro202, and Leu204 is highlighted in orange.</table>

BioMed Research International

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Figure 2

Figure 2: Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors 

Figure 2 | Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors 