BioMed Research International / 2014 / Article / Fig 3

Research Article

Patched Targeting Peptides for Imaging and Treatment of Hedgehog Positive Breast Tumors

Figure 3

Uptake of patched-binding peptides is increased in mammospheres from breast cancer cell lines. (a) Fluorescence microscopy of FITC-labeled peptides A and B in mammospheres from T47-D. (b) Quantification of FITC-peptides A and B uptake in breast cancer cell lines in monolayer and mammosphere cultures. Uptake was significantly higher in cells cultured in mammosphere promoting conditions (3 dimensional cultures) than in those grown in standard monolayer conditions. Significance is represented by asterisk. .

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.