Detection and Antibiotic Treatment of Mycoplasma arginini Contamination in a Mouse Epithelial Cell Line Restore Normal Cell Physiology

Figure 4

Image comparison during Plasmocin treatment. This series of images compare untreated cultures (left column) with Plasmocin-treated cultures (center and right columns) and also compare the effect of passaging cells during treatment (right column) with not passaging (center column). All images have the plane of focus set to the apical surface. Untreated cultures accumulate punctate bodies over time, while the treated cultures (Plasmocin treatment began on Day 7 after plating) instead show the elimination of punctate bodies. Passaging the cells during treatment appears to increase the rate of recovery, and after 3 weeks of Plasmocin treatment the cells that were passaged do not show any punctate bodies present.