Mesenchymal Stem Cell-Induced Doxorubicin Resistance in Triple Negative Breast Cancer
Figure 2
Adipose-derived mesenchymal stem cells-secreted conditioned medium increased BCRP protein expression in MDA-MB-231 cells. Cells were treated with L15 (control medium), MSCM, or MSC-ad conditioned medium for 24 hours and protein expression of (a) P-gp, (b) MRP, and (c) BCRP was examined by Western blotting. Graphs showed mean ± SEM of three independent experiments. to MSCM group. CM, conditioned medium from adipose-derived mesenchymal stem cells (MSC-ad); MSCM, mesenchymal stem cell medium (fresh MSC culture medium).
