Computational Analysis of mRNA Expression Profiles Identifies the ITG Family and PIK3R3 as Crucial Genes for Regulating Triple Negative Breast Cancer Cell Migration

Table 4

25 migration related genes in Asian and non-Asian populations.

	Gene symbol	Multiples of change	Gene description
Up-regulated genes
GSE46581	ITGB1	2.101	Integrin, beta 1
	RGS1	2.231	Regulator of G-protein signaling 1
	AKT3	2.371	v-akt murine thymoma viral oncogene homolog 3
	ETV4	2.103	Ets variant 4
	HTATIP2	2.059	HIV-1 Tat interactive protein 2, 30 kDa
	IGF1	2.231	Insulin-like growth factor 1
	ITGA6	2.295	Integrin, alpha 6
	LEP	2.064	Leptin
	SEMA4D	2.056	Sema domain, immunoglobulin (Ig domain), transmembrane domain and short cytoplasmic domain, (1emaphoring) 4D
GSE33926	PIK3R3	2.006	Phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
	AR	2.106	Androgen receptor
	CLGN	2.004	Calmegin
	TFPI	2.101	Tissue factor pathway inhibitor
Down-regulated genes
GSE46581	CCL21	0.433	Chemokine (C-C motif) ligand 21
	CCL3	0.389	Chemokine (C-C motif) ligand 3
	CAMP	0.464	Cathelicidin antimicrobial peptide
	CD226	0.477	CD226 molecule
	ITGAL	0.478	Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
	ITGAX	0.448	Integrin, alpha X
	TNFRSF	0.368	Receptor- (TNFRSF-) interacting serine-threonine kinase 1
GSE33926	MIA	0.248	Melanoma inhibitory activity
	CDKN2A	0.386	Cyclin-dependent kinase inhibitor 2A
	EN1	0.460	Engrailed homeobox 1
	PITX2	0.476	Paired-like homeodomain 2
	CCR7	0.419	Chemokine (C-C motif) receptor 7