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BioMed Research International
Volume 2014, Article ID 537157, 10 pages
http://dx.doi.org/10.1155/2014/537157
Research Article

NMR-Based Metabolomic Profiling of Overweight Adolescents: An Elucidation of the Effects of Inter-/Intraindividual Differences, Gender, and Pubertal Development

1Department of Food Science, Aarhus University, Kirstinebjergvej 10, 5792 Aarslev, Denmark
2Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, 1958 Frederiksberg, Denmark

Received 29 October 2013; Revised 28 February 2014; Accepted 2 March 2014; Published 27 March 2014

Academic Editor: Claudio Maffeis

Copyright © 2014 Hong Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Two additional figures supporting our results are provided. Figure S1 shows the results of PCA for classification among different Tanner stages and PLSR for correlation between Tanner stages and the metabolome in the plasma data from boys and girls. Figure S2 illustrates the relationship between observed and predicted physical activities by PLSR based on the urine and plasma metabolomes of adolescents and the corresponding loading plots of PLSR.

  1. Supplementary Figures