Are Applied Growth Factors Able to Mimic the Positive Effects of Mesenchymal Stem Cells on the Regeneration of Meniscus in the Avascular Zone?
Gross morphology and histological and immunohistochemical (collagen type II) analysis 3 months after treatment of a meniscal punch defect with a PRP hyaluronan collagen composite matrix construct (a, b, and c) or an empty matrix (control) (d, e, and f) and 3 months after treatment of meniscal tears with a PRP hyaluronan collagen composite matrix construct (g, h, and i) or an empty matrix (j, k, and l). No improvement by treatment of meniscal lesions with PRP could be detected. Magnification bars: (a, d, g, and j): 10 mm; (b, c, e, f, h, i, k, and l): 1 mm.
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