BioMed Research International / 2014 / Article / Tab 2

Research Article

Gender Specific Association of RAS Gene Polymorphism with Essential Hypertension: A Case-Control Study

Table 2

Distributions of allele frequencies in cases and controls stratified gender wise.

GeneAlleleMinor alleleFreq. minor allele caseFreq. minor allele control OR value

AGT M235TM/TM0.2540.3275.5270.699 (0.518–0.943)
 Female0.2260.3587.7970.522 (0.330–0.826)
 Male0.2800.3080.4430.874 (0.588–1.299)0.506
ACE I/DI/DI0.3980.4623.5240.770 (0.586–1.012)0.060
 Female0.4410.4200.1691.091 (0.719–1.656)0.681
 Male0.3570.4898.2650.584 (0.404–0.844)
ACE G2350AG/AA 0.1730.1640.1361.070 (0.746–1.535)0.713
 Female0.1720.2100.8660.780 (0.461–1.318)0.352
 Male0.1740.1351.4441.357 (0.824–2.236)0.229
AGTR1 A1166CA/CC0.3840.4010.2440.933 (0.708–1.230)0.622
 Female0.3630.4140.9850.807 (0.529–1.233)0.321
 Male0.4040.3920.0641.049 (0.726–1.515)0.800

: Chi-square with 1 degree of freedom; OR: odds ratio; : statically significant (alpha value 0.05/4).

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