BioMed Research International / 2014 / Article / Tab 3

Research Article

Gender Specific Association of RAS Gene Polymorphism with Essential Hypertension: A Case-Control Study

Table 3

Distribution of genotype frequencies of RAS gene polymorphisms in patients and control subjects.

SNPsGenotypeCase % ( )Control % ( )OR95% CI value

AGT M235TMM6.1614.22Ref
MT38.3936.972.401.11–5.370.016
TT55.4548.822.621.24–5.76
 MaleMM8.2612.31Ref
MT39.4536.921.590.59–4.520.320
TT52.2950.771.540.58–4.250.340
 FemaleMM3.9217.28Ref
MT37.2537.044.431.21–20.090.011
TT58.8245.685.681.60–25.10

ACE I/DII18.9624.17Ref
ID41.7144.081.210.71–2.070.467
DD39.3431.751.580.90–2.760.087
 MaleII17.4323.08Ref
ID36.7051.540.940.45–2.020.870
DD45.8725.382.391.09–5.270.020
 FemaleII20.5925.93Ref
ID47.0632.101.850.80–4.280.117
DD32.3541.980.970.42–2.250.940

ACE G2350AGG71.0972.51Ref
GA23.2222.271.060.65–1.730.793
AA5.695.211.110.43–2.880.805
 MaleGG71.5677.69Ref
GA22.0217.691.510.42–5.660.472
AA6.424.621.350.67–2.710.359
 FemaleGG70.5964.20Ref
GA24.5129.630.750.37–1.540.400
AA4.906.170.720.16–3.320.620

AGTR1 A1166CAA41.7140.28Ref
AC39.8139.340.980.62–1.530.917
CC18.4820.380.880.50–1.530.622
 MaleAA37.6140.77Ref
AC44.0440.001.030.47–2.240.540
CC18.3519.231.190.65–2.190.930
 FemaleAA46.0839.51Ref
AC35.2938.270.790.39–1.610.484
CC18.6322.220.720.30–1.700.409

: sample size; OR: odds ratio; CI: confidence interval; Ref: reference; : statically significant.

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